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Disciplina de Bioquímica e Hematologia Clínicas

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Bioquímica - Stryer

How these molecules arose livro bioquimica a matter of conjecture, but experiments have established that they could have formed under livro bioquimica prebiotic conditions. Evolution Requires Reproduction, Variation, and Selective Pressure The next major transition in the evolution of life was the formation of replicating molecules.


Replication, coupled livro bioquimica variation and selective pressure, marked the beginning of evolution. Variation was introduced by a number of means, from simple base substitutions to the duplication of entire genes.


RNA appears to have been an early replicating molecule. Furthermore, some RNA molecules possess catalytic activity. However, the range livro bioquimica reactions that RNA is capable of catalyzing is limited.

Livro bioquimica Documento PDF

With time, the catalytic activity was transferred to proteins— linear polymers of the chemically versatile amino acids. RNA directed livro bioquimica synthesis of these proteins and still does in modern organisms through the development of a genetic code, which relates base sequence to amino livro bioquimica sequence.

Energy Transformations Are Necessary to Sustain Living Systems Another major transition in evolution was the ability to transform environmental energy into forms capable of being used by living systems.

ATP serves as the livro bioquimica energy currency that links energy-yielding reactions with energy-requiring reactions. ATP itself is a product of the oxidation of fuel molecules, such as amino acids and sugars. With the evolution of membranes—hydrophobic barriers that delineate the borders of cells—ion gradients were required to prevent osmotic crises.

These gradients were formed at the livro bioquimica of ATP hydrolysis. Later, ion gradients generated by light or the oxidation of fuel molecules were used to synthesize ATP. Irene Jesus Liver - central processing Glucose 6-phosphate metabolism in the liver Irene Jesus Metabolism of amino acids in the liver Irene Jesus Metabolism of fatty acids in livro bioquimica liver Irene Jesus Portal vein communicates Regulates the distribution of dietary fuels polymers converted to monomers Site for fuel interconversion and production of precursors.

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