Med Monatsschr Pharm. Sep;30(9); quiz [Sialorrhea--causes and treatment options]. [Article in German]. Reiss M(1), Reiss G. Sialorrhea (drooling or excessive salivation) is a common problem in neurologically impaired children (i.e., those with mental retardation or cerebral palsy) and in adults who have Parkinson's disease or have had a stroke. It is most commonly caused by poor oral and facial muscle control. Hypersalivation, or increased saliva, can be caused by overproduction or decreased clearance of saliva. There are many medical conditions.


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Outlook Some causes of hypersalivation may clear up over time without treatment.

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Such causes include pregnancy, anxiety, and minor injuries. Other sialorrhea causes can pose more serious medical challenges. This category includes neurological causes and nerve disorders.

If chronic conditions are the cause, treatment may include lifelong management of a person's hypersalivation. Caretakers praise patients for not sialorrhea causes or require them to wipe their faces when they forget to swallow.


Over a six-week period, patients were treated sialorrhea causes times with needles placed in five locations in the tongue. Further study of the effectiveness of acupuncture in the treatment of sialorrhea is warranted.

If sialorrhea continues sialorrhea causes interfere with the patient's health and quality of life after non-invasive measures have been tried, medication, radiation, and surgical therapy should be considered. Glycopyrrolate is best sialorrhea causes for its drying properties and a limited central nervous system activity.

An example of an exogenous source causing stimulation is chewing. Sialorrhea can be either due to increased production of saliva idiopathic or drug-induced or related to failure of mechanisms that clear and remove saliva sialorrhea causes the oral cavity.

Disturbance in the coordination of orofacial and palate—lingual musculature is one mechanism that can lead to pooling of saliva in anterior portion of mouth.


Ultimately, muscle incoordination inhibits the initiation of the swallow reflex, thereby further disrupting the path of saliva from sialorrhea causes mouth to the oropharynx [ 10 ]. Salivary secretion is regulated sialorrhea causes a reflex arch which has various influences.

The afferent branch consists of chemoreceptors in taste buds and mechanoreceptors in the periodontal ligament. Afferent innervations of cranial nerves V, VII, IX and X also play a role by carrying impulses to salivary nuclei in the medulla oblongata [ 11 ].


Efferent influences are mainly parasympathetic via cranial nerve VII sialorrhea causes control the submandibular, sublingual, and other minor glands, and CN IX which influences the parotid gland [ 11 ]. Sialorrhea occurring with neurologic sialorrhea causes is usually due to impaired swallowing as a result of impaired neuromuscular function.


The toxin paralyzes the nerves sialorrhea causes muscles in the area, preventing the glands from producing sialorrhea causes. This effect will wear off after a couple of months, so you will likely need to return for repeat injections.

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